SNPs previously reported to be associated at the genome-wide level of significance (p<5×10−8) with alcohol consumption-related traits, including the maximum quantity of drinks consumed in a 24 hour period (MaxDrinks), were examined for association in this sample. When several SNPs were reported at a genome-wide level of significance at the same locus/gene, we chose the SNP with the most significant p-value. In total, 14 SNPs other than our top GWA findings were selected (Supplementary Table 1), including 7 SNPs previously associated in European ancestry populations,26–29 4 SNPs in Asian ancestry populations,41–43 and 3 SNPs in African ancestry populations.26 As two candidate SNPs (rs2309169 and rs200475889) were not in 1000 Genomes Project (phase I) and so could not be imputed, 12 SNPs remained for association analysis.
