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Chunk #37 — Discussion

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A Novel Approach to High-Quality Postmortem Tissue Procurement: The GTEx Project.
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The project has added the collection of frozen tissue samples for a limited number of tissue types based on feedback from a request for information (RFI) regarding the potential uses of stored GTEx biospecimens (http://grants.nih.gov/grants/guide/notice-files/NOT-RM-12-028.html). Adding frozen biospecimens will increase the utility of the biospecimen set for the research community in terms of being able to compare the GTEx tissue directly to past and future studies with frozen tissue since PAXgene preserved tissue is not yet widely utilized. The novel infrastructure put in place by BBRB and its partners is an essential part of the groundbreaking GTEx scientific project, which has the potential to change our understanding of gene regulation and how gene interactions contribute to disease development.