Significant age-by-sex interactions (p<0.05, uncorrected) were also found in several brain regions (Figure 5). Further, the Pearson's correlation analysis revealed the correlations between age and the regional nodal parameters in each sex group. A significant negative correlation with age (p = 0.005) in the node degree in the left SPG was found in the girls, whereas a positive correlation with age (p = 0.537) was found in the boys (Figure 5A). The girls showed positive correlation with age (p = 0.330) in the node efficiency in the left cuneus (CUN), whereas the boys showed negative correlation with age (p = 0.114) (Figure 5B, left). A significant negative correlation with age (p = 0.002) in the node efficiency in the left SPG was found in the girls, whereas the boys showed positive correlation with age (p = 0.329) (Figure 5B, right). A significant positive correlation with age (p = 0.034) in the node betweenness in the left REC was found in the boys, whereas the girls showed no change with age (p = 0.602) (Figure 5C, left). The girls showed significant
