the 5,6EET regioisomer, in accordance with results from Snider et al. demonstrating the potency of 5,6-EET-EA [72]. Though the affinity of 19µM for CB2 is weak we tested if either a CB1 or CB2 antagonist would block sEHI mediated anti-hyperalgesia. Predictably, the CB2 but not CB1 antagonist blocked the sEHI anti-hyperalgesia (Figure 4).
