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Chunk #15 — Methods — Statistical analyses

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Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.
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Phenome-wide association studies were conducted with the PheWAS R package v0.12 [27]. We required phecodes to have at least 100 cases, and included covariates for sex, median age across the EHR, genotyping batch, and the first 10 principal components of ancestry.