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Chunk #61 — STAR★METHODS — QUANTIFICATION AND STATISTICAL ANALYSIS — Gene finding analysis in fastBAT — Fine mapping of SNPs

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Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
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and defined 95% credible causal sets of variants as the minimum set of variants whose PIPs summed to >=0.95. We mapped credible causal sets to 19,878 protein coding genes. We defined high-confidence genes as those containing all variants within the credible causal set within the gene body, and additionally listed all genes at least partially overlapping the credible causal set. We performed analyses on the full, multiple ancestry meta-analysis, and additionally on the European ancestry subset. Estimates of LD (for clumping and for S-LDSC) used European ancestry reference panels; as such, multiple ancestry analyses should be considered exploratory.