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Chunk #34 — 5. Neurobehavioral Hypotheses

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The neurobiology of adolescence: changes in brain architecture, functional dynamics, and behavioral tendencies.
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The triadic node model (Ernst et al., 2006) posits that the specific developmental trajectory of brain regions subserving affective processing and cognitive control, and the balance between them, may underlie the risk-taking propensity of adolescents. This model is also based on the activity of three nodes corresponding to specific brain regions. In this case a node responsible for reward approach (ventral striatum) is in balance with a punishment-avoidance node (amygdala). A modulation node (prefrontal cortex) affects the relative influence of these countervailing forces, and risky behavior will result from a final calculus favoring approach. According to this model, in situations involving some probabilistic trade-off between appetitive and aversive stimuli, the approach node is more dominant in adolescents. Hyperactivity or hypersensitivity of a reward-approach system might otherwise be adjusted by activity in portions of the prefrontal cortex, however its underdevelopment in adolescents does not permit adequate self monitoring and inhibitory control (Ernst and Fudge, 2009).