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Chunk #55 — Discussion

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Guidelines for Evaluating the Comparability of Down-Sampled GWAS Summary Statistics.
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Providing public summary statistics to the wider research community is crucial to facilitating open science and advancing behavioral and biomedical research. The first step in this process should be to evaluate the comparability of down-sampled summary statistics and their restricted data counterparts. Herein, we provide a systematic approach to investigators who resort to sharing down-sampled GWAS summary statistics and recommend they report these analyses as accompanying documentation to facilitate open science and data sharing.