10), supporting a scenario in which a second admixture event between the Aeta and Denisovans happened after the separation of the Aeta and Melanesians. Two distinct Denisovan admixture events are most consistent with Homo sapiens and Denisovans interacting within southeast Asia23, making it likely that admixture occurred within Sundaland (Fig. 2b) or even farther east24,25.