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Chunk #16 — Results — Classification Analysis of Whole-Brain Functional Connectivity in Children and Young-Adults

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Development of large-scale functional brain networks in children.
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We examined differences in whole-brain functional connectivity patterns between children and young-adults. The connectivity patterns,- correlation values of 4,005 pairs of anatomical regions, were used as features in a support vector machine (SVM) classifier (see Text S1). We found that connectivity patterns in children could be distinguished from those in young-adults with accuracies ranging from 89% to 91%, with the highest accuracy in scale 3 (see Table 2). This suggests that functional connectivity patterns at the whole-brain level in children are significantly different from those in young-adults. We report below the nature of these developmental changes in the context of hierarchical and regional organization of brain connectivity.