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Chunk #15 — Materials and Methods — Procedures

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ADH1B*3 and response to alcohol in African-Americans.
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The alcohol administration and assessment were conducted in a private office, with a semi-recumbent chair, separate from that used for interviews. This office was equipped with a vital signs monitor and computer. Participants were assessed prior to beverage consumption, in 15 minute intervals for the first hour following consumption, and 30 minute intervals thereafter (i.e., 15, 30, 45, 60, 90, 120, and 150 minutes). Between 8:30 and 9:00 a.m., baseline measures were taken. At 9:00 a.m., participants received an alcoholic beverage. Participants received a dose of alcohol equivalent to 0.72g/kg of alcohol for males and 0.65g/kg for females. This dose was designed to produce a peak BrAC of approximately 0.075 to 0.080 mg% for both males and females (Sher & Walitzer, 1986). The alcohol drinks were made using 50% alcohol (vodka), in 20% solution with non-caffeinated soda (tonic). Beverages were consumed over a 15-minute period. At approximately noon, each participant was provided lunch.