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Chunk #1 — Introduction

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The association between depressive symptoms from early to late adolescence and later use and harmful use of alcohol.
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An ‘internalizing’ subtype of alcohol dependency has been described previously [5, 6] although much of this earlier work has been conducted in adults. There is evidence, however, that a positive relationship between depressive symptoms and alcohol use/misuse becomes evident earlier in life, and extends to subclinical levels of problems. For example, using a method similar to growth curve modelling, Marmorstein [3] examined a population-based sample of adolescents and young adults, and found that subclinical depressive symptoms and alcohol problems had reciprocal effects on one another during this period, with some differences across the sexes. A study of younger adolescents, using an auto-regressive cross-lag model across four waves of data, suggested that depressive symptoms were positively associated with later alcohol use [7]. Many previous studies [8–11] of the association between depressive symptoms and alcohol use rely on cross-sectional data or include only two time points. Data from longitudinal studies, though not as widely available, are preferable because they allow additional questions to be addressed, such as whether the changes in depressive symptoms over time are related to alcohol use. An individual