patients with ASDs has been reported (Maussion et al., 2008). DDX6 lies at 121 cM on chromosome 11; this locus may harbor genes associated with smoking-related behavior (Li et al., 2008). We have previously found suggestive linkage for DSM-IV defined nicotine withdrawal at 123 cM (LOD=1.68; (Pergadia et al., 2009)), near this SNP. Others have reported linkage (LOD=1.97) for DSM-IV ND at 109 cM (Gelernter et al., 2007).
