The Lifelines COVID-19 Questionnaire was launched within the Lifelines Cohort Study, a large prospective population-based prospective cohort study and biobank in the three northern provinces of the Netherlands, examining in a three-generation design the biomedical, socio-demographic, behavioural, physical and psychological factors contributing to the health and disease of 167,729 individuals living in the north of the Netherlands (Hoveling et al., 2021) -composition and characteristics of the sample have been discussed elsewhere (Klijs et al., 2015, Scholtens et al., 2015).