Unlike GBD 1990, which estimated incident-YLDs, GBD 2010 estimated prevalent-YLDs by multiplying the prevalence of a given condition by its disability weight, and without age-weighting and discounting, both of which had been used in earlier GBD studies[26]. As these, in combination with other factors, such as newly derived disability weights, changed the DALY metric from GBD 1990, the YLDs in GBD 2010 were recalculated for 1990, as well as for 2005 and 2010, to facilitate the investigation of changes in burden across time.