Because LDSC requires single ancestry summary statistics as input, analyses were conducted separately for EA and AA samples (see online Supplementary Table S1). For the EA samples, pre-computed LD scores came from the 1000 Genomes Project Europeans (https://data.broadinstitute.org/alkesgroup/LDSCORE/eur_w_ld_chr.tar.bz2). For the AA samples, the AA specific LD scores (subset under UKBB.AFR prefix) from the UKB pan-ancestry LD scores (Pan-UKB team; https://pan.ukbb.broad-institute.org, 2020) were used.
