In this study, single-point analyses revealed three novel regions (on chromosomes 12q13, 12q24 and 16p13) showing strong evidence of association (P<5×10-7; Table 3). Four further regions attained similar levels of significance either through multilocus analyses (chromosomes 4q27 and 12p13: Table 3, Supplementary Fig. 12), or through the combined analysis of autoimmune cases (chromosomes 18q11 and the 10p15 CD25 region: Table 3, Supplementary Fig. 13). The associations with T1D for chromosomes 12q13, 12q24, 16p13 and 18p11 have been confirmed in independent and multiple populations10.
