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Chunk #45 — Conclusions and Future Directions

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The error-related negativity (ERN) and psychopathology: toward an endophenotype.
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Although many psychiatric disorders can be categorized into the internalizing-externalizing dimension, psychotic disorders such as schizophrenia do not fit well within this model – and questions remains as to whether or not psychotic disorders represent an entirely unique dimension (see Krueger & Tackett, 2003). Interestingly, the literature suggests that individuals with schizophrenia represent a unique dimension: in contrast with the internalizing and externalizing dimensions characterized by increased and decreased error-sensitivity, respectively, schizophrenia is characterized by a general inability to self-monitor (Malenka, Angel, Hampton, & Berger, 1982; Stirling, Hellewell, & Quraishi, 1998).