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Chunk #1 — Introduction

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Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review.
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alcohol in different social groups and across time and location, and these can vary even within an individual’s life. Average drinks per week is widely studied, but is highly skewed, with most people consuming less than 2 drinks per week and with a small fraction consuming very large quantities. It does not capture the pattern of drinking (e.g., bingeing). There is only a modest genetic correlation between average drinks per week and AUD (from 0.37 – 0.70) (Walters et al., 2018).