We conducted haplotype analyses for markers rs16969968, rs1051730, and rs2869546 since these markers showed significant or marginal associations in both VAANX-ND and VAFTND samples. In these analyses, we found that the major haplotypes were the same in the two samples, and that their frequencies were similar. In association analyses, haplotype A-A-T or 2-2-1 was significantly associated FTND scores in both samples (Table IV). These results were consistent with that observed in the single marker analyses.