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Chunk #32 — Genetic linkage studies

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The genetics of obsessive-compulsive disorder: a review.
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In a second set of analyses of 219 families, Samuels et al139 examined whether compulsive hoarding behavior was linked to different markers across the genome. These investigators reported suggestive evidence for linkage for D14S588 (KAC(all)=2.9) on chromosome 14. When families which included two or more hoarding relatives were analyzed separately, the Kong and Cox LODall score increased to 3.7.