Chunk #8 — Results

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Combined analysis of circulating β-endorphin with gene polymorphisms in OPRM1, CACNAD2 and ABCB1 reveals correlation with pain, opioid sensitivity and opioid-related side effects.

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The genotype frequencies of the minor allele of OPRM1, ABCB1 and CACNA2D2 are presented in Table 1, and were in accordance with Hardy-Weinberg equilibrium [31].