Ten brain regions, five in each hemisphere, were selected as seed regions of interest (seed ROIs) in this study (Figure 1, Table 1). These ROIs were bilateral nucleus accumbens (NAc), amygdala (Amy), dorsal anterior cingulate cortex (Broadman area (BA) 24/32), and orbital frontal cortex (OFC, including the lateral areas, BA 11/47, and the medial areas, BA 11/12). These regions were defined for each participant anatomically as follows. First, a set of masks corresponding to the regions listed above were defined in a standardized coordinate system of Talairach atlas (Talairach et al., 1992) and cortical structures of a standardized brain. Subsequently, these masks were transformed, according to the spatial transformation between the anatomic data and the Talairach space, onto to the image space of each participant and were modified according to individual brain’s cortical structures by referencing to the anatomic boundaries in the high-resolution three-dimensional structural images.
