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Chunk #5 — INTRODUCTION

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Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genome-wide analysis.
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Here we focus on common CNVs and report a genome-wide CNV detection and association analysis for early-onset extreme obesity using two GWAS discovery data sets (family-based and case–control, altogether 2160 genotyped individuals) and an additional replication sample of 365 independent obesity trios (Fig. 1).