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Chunk #46 — Discussion

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Genome-wide time-to-event analysis on smoking progression stages in a family-based study.
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In conclusion, we detected genome‐wide significant association between SNPs and three transitions in smoking behavior in a Finnish twin family sample. The interpretation of our findings should be cautious before robust evidence of replication is obtained. Our results are valuable for guiding follow‐up functional analyses, provide valuable clues into the etiology of smoking behavior, and encourage further studies utilizing time‐to‐event phenotypes in addictive behavior.