heroin-dependent users might be a consequence of their taking these substances to feel better, to promote sleep, to relieve depression, trait anxiety and related symptomatology and to avoid withdrawal symptoms [29, 34]. The finding that MA dependent users (MDs and H/MDs) had higher rate of hallucination use disorders, but not for HDs, confirmed the transition from traditional drugs (such as opioid or sedative) to synthetic drugs. The trend of illicit drug use was strongly influenced peoples’ choice on drugs.