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Chunk #45 — Methods — Kinship coefficient estimation

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The UK Biobank resource with deep phenotyping and genomic data.
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To ensure we were not overestimating the number of related pairs, we inferred related pairs (within a subset of the data) using a different inference method implemented in PLINK (‘-genome’ command; https://www.cog-genomics.org/plink2) and confirmed 100% of the twins, parent-offspring and sibling pairs, and 99.9% of pairs overall (Supplementary Information).