Association for cis- and trans-eQTL was tested with a non-parametric Spearman's rank correlation. For directly genotyped SNPs we coded genotypes as 0, 1 or 2, while for imputed SNPs we used SNP dosage values, ranging between 0 and 2. When a particular probe-SNP pair was present in both the HT12 and H8v2 datasets, an overall, joint p-value was calculated using a weighted (square root of the dataset sample number) Z-method.
