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Chunk #7 — Methods — Study population

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The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum.
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A sample of 4738 controls from the LifeGene cohort was available for this study. LifeGene is a prospective population-based cohort of around 50,000 individuals in Sweden (23). The samples were available in four batches: LifeGene-EGOS (n=1444), LifeGene-NORDiC (n=500), LifeGene-ANGI-Wave-1 (n=1500), and LifeGene-ANGI-Wave-2 (n=1500). LifeGene-ANGI controls were previously used in a study of anorexia nervosa (AN) (24); they were mostly females (2935 females and 65 males), and all individuals with a diagnosis of AN were previously removed from this batch. All controls were genotyped using GSA.