Finally, major depression had significant negative genetic correlations with data from two studies of educational attainment, which while often considered at the genetic level as proxy measures of intelligence also likely includes more complex personality constructs. With this in mind, it is relevant to note that the rg between major depression and IQ61 was not significantly different from zero, despite an the rg between years of education and IQ of 0.7, implying complex relationships between these traits worthy of future investigation. We also found significant positive correlations with multiple measures of adiposity, relationship to female reproductive behavior (decreased age at menarche, age at first birth, and increased number of children), and positive correlations with coronary artery disease and lung cancer.
