Historically, level of response (ie, a low response) has been assessed through various measurements, which include level of change in subjective feelings of intoxication, motor performance, hormone levels, and/or electrophysiological measures observed at specific blood alcohol concentrations, or by a self-report of the number of drinks required for specific effects.16-18 The effects of ethanol can be measured by the use of the alcohol challenge test, where subjects are typically given three to five standard drinks to be consumed over approximately 10 minutes.13,14,16
