because the common variants did not completely capture the phenotypic variance driven by the uncommon variants. The parameter α also determines the study wide FSTC according to FSTC = (0.15(1-α) + 0.25α) (see Online Methods). The results shown in Table 2 use the correct value of α, and hence the estimates of h2 are unbiased. However, if we incorrectly assume that α=0 when it does not, then h2 will be biased by factor of (0.15(1- α) + 0.25α)/0.15. We describe this (and other potential sources of bias) in detail in the Discussion.
