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Chunk #11 — Methods and Materials — Statistical Analyses

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An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype.
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We selected the genome wide significant SNPs in two loci from the discovery stage for replication. After analyzing these data, we performed a P value based meta-analysis combining all replication samples. Further, we analyzed the results of the discovery and all replication samples weighting for number of cases.