the nearby marker D4S2394, which had nominal significance (point-wise P = 0.013) in the later Tsuang study. In the linkage study of Gelernter, which used 409 STR markers in 393 families, a linkage peak at D17S785 was found (LOD = 3.06, empirical P = 0.0002) (Gelernter et al., 2006). Variant rs9271, which was ranked sixth in Table 2 in our current study and was found to be nominally associated with heroin addiction in the Caucasians (point-wise P = 0.0003), is located six million nucleotides from D17S785.
