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Chunk #16 — MATERIALS AND METHODS — Zygosity Determination and Genotyping

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Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?
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yes

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less than 10−4 (i.e., resulting in 99.99% zygosity certainty) (Nyholt, 2006). Additionally, most pairs were genotyped, as part of ongoing linkage studies, at a minimum of 20 (maximum of 1369) microsatellite markers. Only 16 pairs had fewer than 20 markers for one or both co-twins and consequently have not had zygosity confirmed through microsatellite genotyping. Of these, 6 pairs have been checked for blood group.