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Chunk #36 — 6. Association Test — 6.1 Single Locus Analysis

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Chapter 11: Genome-wide association studies.
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Dichotomous case/control traits are generally analyzed using either contingency table methods or logistic regression. Contingency table tests examine and measure the deviation from independence that is expected under the null hypothesis that there is no association between the phenotype and genotype classes. The most ubiquitous form of this test is the popular chi-square test (and the related Fisher's exact test).