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Chunk #2 — Introduction — Associations between ADH1B and Alcohol-Related Phenotypes

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Childhood adversity moderates the effect of ADH1B on risk for alcohol-related phenotypes in Jewish Israeli drinkers.
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phenotypes have been shown in Israeli Jews (Hasin et al., 2002; Neumark et al., 1998), including association with maximum drinks consumed in a 24-hour period (“Maxdrinks”) and AUD severity in recent work in a large household sample (Meyers et al., 2013). This large sample of Jewish Israelis presents an important opportunity to investigate whether the association of ADH1B and alcohol phenotypes is moderated by environmental factors.