A similar meta-analysis was conducted using self-reported (SR)-Depression (see Methods) from MVP, conducted on 210,331 individuals who completed survey items on self-reported diagnosis of depression by a medical professional; the total meta-analysis with the traits from PGC, UK Biobank and FinnGen included 1,114,383 subjects. A third analysis considered depressive symptoms from the Patient Health Questionniare-2 (PHQ-2),42 a 2-item scale which assesses depressive symptoms within the prior two weeks (Table S4). For this phenotype, data were only available from MVP and UK Biobank, with a total sample of 286,821 European participants.
