excess of enriched categories of genes with p-values <0.005 and 0.01 consistently in both OZALC-NAG and SAGE studies (Table 2). Applying the same criteria described above, we analyzed the categories with category-specific p-values <0.01. Our replication strategy was to evaluate the subset of categories of genes that were significant for both the OZALC-NAG and the SAGE studies in the ARIC study (p-value<0.05) (See Table 2 for the number of common categories of genes between the two studies and its statistical significance).
