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Chunk #27 — Methods — Genomic Regulatory Blocks

Source
Obesity-associated variants within FTO form long-range functional connections with IRX3.
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yes

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The hg19 GWAS catalog from the UCSC Genome browser was downloaded and the tagging SNPs contained in GRBs with more than 1 gene (making SNP assigning doubtful) were kept for further annotation. SNPs occurring in exons were removed. The nearest gene was considered to be the RefSeq gene whose transcription start site was the nearest, or the gene where the SNP is contained.