Chunk #109 — Determinants of BAC — Alcohol-drug interactions — Therapeutic agents targeting ethanol metabolism — Cyanamide (calcium carbimide):

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Recent advances in alcohol metabolism: from the gut to the brain.

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This drug is used in parts of Europe, Canada, and Japan, and it also inhibits ALDH via its active metabolite, nitroxyl (299). It has a shorter half-life than disulfiram but carries a higher risk of liver injury and is thus not frequently prescribed, and it is not US FDA-approved.