This marker was also among the top SNPs in a GWAS of conduct disorder symptoms, which involved 909 patients with attention deficit disorder aged between five and 17 years and their parents (p=3.44E–5 (Sonuga-Barke, Lasky-Su, Neale et al. 2008); risk allele A [http://www.genome.gov/gwastudies]). Conduct disorder and AD are frequently comorbid, and twin studies support the hypothesis that conduct problems in children and antisocial behavior in adults are correlated genetically with AD (Pickens, Svikis, McGue et al. 1995; Slutske, Heath, Dinwiddie et al. 1998).
