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Chunk #8 — METHODS — RELATIONHIP ESTIMATION

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Case-control association testing in the presence of unknown relationships.
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yes

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The simplest summary of the degree of a pairwise relationship is the kinship coefficient, ϕ, which is the probability that a pair of homologous alleles chosen from two individuals are identical by descent (IBD). In this section, we briefly describe how to estimate ϕ by estimating the set of three k-coefficients in a non-inbred population [Crow and Kimura, 1970].