We examined the cis associations between the 97 GWS SNPs and expression of nearby genes in whole blood, lymphocytes, skin, liver, omental fat, subcutaneous fat and brain tissue48–55 (Supplementary Table 23). Conditional analyses were performed by including both the BMI-associated SNP and the most significant cis-associated SNP for the given transcript. Conditional analyses were conducted for all data sets, except the brain tissue data set due to limited power. To minimize the potential for false-positives, only cis associations below a study-specific FDR of 5% (or 1% for some data sets), in LD with the peak SNP (r2 > 0.7) for the transcript, and with conditional P > 0.05 for the peak SNP, are reported (Extended Data Table 2).
