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Chunk #31 — Discussion

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A neurophysiological deficit in early visual processing in schizophrenia patients with auditory hallucinations.
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Auditory hallucinations, considered a hallmark symptom of schizophrenia (Wible et al., 2009), involve activation in auditory association cortex as well as non-sensory cortical and subcortical regions and interfere with cognitive processing (reviewed by Allen, Laroi, McGuire, & Aleman, 2008). Although the mechanism responsible for cognitive interference remains unknown, the reduction of N1 sink amplitude to words and faces during WM and RM paradigms has implications for understanding its basis.