for approach 1 (converge then cluster) are thus 0.39 and 0.11, since this approach requires nominally positive results for the same SNP from both samples. Statistical power for the analysis of these samples can also be calculated using “gene detective” [25]; this power rises from 0.1 to ca. 0.9 as risk to a sib of an affected individual (λs) rises from 1.2 to 2.5 [35].