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Chunk #53 — Discussion

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Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence.
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The findings presented in the current report thus add the strong evidence for involvement of variants in several individual genes, add to the ongoing consideration of methods for comparing GWA datasets and enhance understanding of genetic underpinnings of human addiction. For addictions, as for many complex disorders, such data provides an increasingly rich basis for improved understanding and for personalized prevention and treatment strategies.