The replicated SNP rs3778150 was originally implicated as a cis-eQTL SNP at P=0.042 in BrainCloud European Americans (Table 1): the C allele being associated with reduced OPRM1 expression (Figure S4A). Rs3778150 was not significantly implicated in the African Americans only (P=0.38, Figure S4B) or all BrainCloud participants (P=0.089, Figure S4C).
