prescriptions, given their overlapping indications with benzodiazepines and no known association with drug-related poisoning or mortality in adults. The lack of association between SSRI prescriptions and poisoning is notable, suggesting that increased odds of poisoning following receipt of benzodiazepine is more attributable to benzodiazepines as opposed to underlying conditions leading to a benzodiazepine or SSRI prescription. Finally, our findings were pharmacologically-informed, using the high statistical power of the MarketScan data to identify subgroups of patients receiving buprenorphine who may be at elevated risk of treatment failure, such as those taking short-acting benzodiazepines and higher-potency agents.
