not cause lung cancer.40Table 2Hazard ratios for major cardiovascular outcomes in current drinkers, without and with adjustment for usual levels of systolic blood pressure, high-density-lipoprotein cholesterol, or body-mass indexAll strokeMyocardial infarctionCoronary disease excluding myocardial infarctionHeart failureDeaths from other types of cardiovascular diseaseSubset of participants with measurement of systolic blood pressureCohorts/events70/11 29773/13 51946/778939/266844/1019Basic adjustment*1·16 (1·11–1·22)0·95 (0·91–0·99)1·06 (1·00–1·12)1·11 (1·04–1·18)1·16 (1·06–1·27)Plus adjustment for systolic blood pressure1·10 (1·06–1·14)0·91 (0·87–0·94)1·03 (0·97–1·10)1·08 (1·02–1·15)1·14 (1·03–1·25)Subset of participants with measurement of high-density-lipoprotein cholesterolCohorts/events56/798261/991136/360829/188634/690Basic adjustment*1·16 (1·10–1·23)0·93 (0·88–0·97)1·07 (0·98–1·17)1·09 (1·00–1·19)1·22 (1·06–1·40)Plus adjustment for high-density-lipoprotein cholesterol1·17 (1·11–1·22)1·00 (0·96–1·04)1·13 (1·05–1·22)1·14 (1·01–1·27)1·22 (1·08–1·38)Subset of participants with measurement of body-mass indexCohorts/events68/11 73371/14 21743/776136/256642/1035Basic adjustment*1·15 (1·10–1·19)0·95 (0·91–0·98)1·06 (1·02–1·12)1·12 (1·04–1·20)1·16 (1·06–1·27)Plus adjustment for body-mass index1·14 (1·10–1·18)0·94 (0·91–0·97)1·06 (1·01–1·12)1·10 (1·03–1·16)1·16 (1·06–1·27)Data are hazard ratio (95% CI) per 100 g per week higher usual alcohol consumption, unless otherwise indicated. Analyses were restricted to individuals with basic adjustment variables plus the additional variable. Studies with fewer than five events were excluded from the analysis of each outcome.*Basic adjustment includes age, smoking, and history of diabetes, and stratification by sex and centre.
